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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
LLL-12 Influence on tumor growth Tumor volume 5.00 mg/kg MDA-MB-231 (xenograft) Mus musculus
LLL-12 Influence on tumor growth Tumor volume 2.50 mg/kg U87 Mus musculus
LLL-12 Influence on tumor growth Tumor volume 5.00 mg/kg U87 Mus musculus
LLL-12 Influence on protein activity in tumor tissue Western Blot 5.00 mg/kg MDA-MB-231 (xenograft) Mus musculus p-STAT3 (Y705)
LLL-12 Influence on protein activity in tumor tissue Western Blot 5.00 mg/kg MDA-MB-231 (xenograft) Mus musculus STAT3
LLL-12 Influence on protein activity in tumor tissue Western Blot 5.00 mg/kg MDA-MB-231 (xenograft) Mus musculus
LLL-12 Influence on protein activity in tumor tissue Western Blot 5.00 mg/kg MDA-MB-231 (xenograft) Mus musculus
LLL-12 Influence on tumor growth Tumor volume 5.00 mg/kg SNU398 (xenograft) Mus musculus nude mice
LLL-12 Influence on tumor growth Body weight 5.00 mg/kg SNU398 (xenograft) Mus musculus nude mice
LLL-12 Influence on tumor growth Tumor volume 5.00 mg/kg OS-33 (xenograft) Mus musculus
LLL-12 Influence on tumor growth Tumor volume 5.00 mg/kg SJSA (xenograft) Mus musculus
LLL-12 Influence on protein activity in tumor tissue Western Blot 5.00 mg/kg SJSA (xenograft) Mus musculus p-STAT3 (Y705)
LLL-12 Influence on protein activity in tumor tissue Western Blot 5.00 mg/kg SJSA (xenograft) Mus musculus STAT3
LLL-12 Influence on protein activity in tumor tissue Western Blot 5.00 mg/kg SJSA (xenograft) Mus musculus